Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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2,926 – 2,940 of 3,759 results

2,926

Ambeed 4 4 6Dimethoxy1 3 5triazin2yl

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium tetrafluoroborate, 293311-03-2, 95%

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2,927

Ambeed 4Amino2bromopyrimidine

4-Amino-2-bromopyrimidine, 1160994-71-7, 95%

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2,928

Apexbio Technology LLC [Ser25] Protein Kinase C (19-31) 136795-05-6 5mg

[Ser25] Protein Kinase C (19-31) (CAS 136795-05-6) is an oligopeptide derived from the pseudosubstrate regulatory domain (amino acids 19-31) of Protein Kinase C alpha (PKC ) modified by substitution of alanine with serine at residue 25 Its sequence is Arg-Phe-Ala-Arg-Lys-Gly-Ser-Leu-Arg-Gln-Lys-Asn-Val with a molecular weight of 1559 82 and molecular formula C67H118N26O17 It acts as a PKC substrate peptide enabling in vitro measurement of kinase enzymatic activity via serine phosphorylation PKC enzymes participate in diverse cellular processes including adhesion transformation cell cycle control and calcium signaling making this peptide an important tool for kinase activity studies and intracellular signaling research

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2,929

Cayman Chemical 4-HydroxyquInolIn 5g

A quinoline alkaloid; is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules; has been used as a precursor in the synthesis of compounds with antibacterial activity; has been used as a fluorescent detection reagent for iron(III) in bovine liver samples

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2,930

Medchemexpress LLC SRI 6409-94 | 127697-58-9 | 99.25% | 379.49 | 5 MG

SRI 6409-94 is an orally active Ro 13-6298 analogue that is teratogenic. It serves as a molecular tool to study the effect of the three-dimensional configuration of retinol on teratogenic activity.

Orally active compound.
Aids in the study of retinol's three-dimensional configuration and its effect on teratogenic activity.
Induces deformed offspring in a dose-dependent manner in virgin female outbred Syrian golden hamsters.
Leads to significant reductions in mean fetal body weight and the number of ossified skeletal districts in studies.
Purity of 99.25%.
Available in solid form with a light yellow to brown color.
Stable for 3 years at -20°C as a powder, and 2 years at 4°C as a powder.
In solvent, stable for 6 months at -80°C and 1 month at -20°C.

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2,931

Medchemexpress LLC Pyrroloquinoline quinone disodium salt | 122628-50-6 | 98.0% | 374.17 g/mol | C14H4N2Na2O8 | 50 MG

Pyrroloquinoline quinone disodium salt is the disodium salt form of the redox cofactor PQQ supplied for research and analytical applications. The material is a pink to red solid used in studies of metabolism, oxidative stress, and cellular signaling. It is provided as a small powdered reagent with recommended sealed storage to preserve stability.

Redox co-factor used in metabolic and oxidative stress research.
High purity suitable for analytical and biological applications.
Pink to red solid that is easy to weigh and handle.
Stable when stored sealed and protected from moisture.
Available in small powder pack sizes for laboratory use.

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2,932

Medchemexpress LLC CR-1-31-B | 1352914-52-3 | >98.38% | 507.53 | 25 MG

CR-1-31-B is a synthetic rocaglate and a potent eIF4A inhibitor. It effectively inhibits eIF4A by disrupting the interaction between eIF4A and RNA, thereby impeding protein synthesis initiation. This compound also interferes with the association of Plasmodium falciparum eIF4A (PfeIF4A) with RNA and has been shown to induce apoptosis in neuroblastoma and gallbladder cancer cells.

Inhibits eIF4A by disrupting RNA interaction
Impairs protein synthesis initiation
Interferes with PfeIF4A association with RNA
Induces apoptosis in neuroblastoma and gallbladder cancer cells
Inhibits MUC1-C translation
Decreases MUC1-C abundance
Sensitizes gallbladder cancer cells to TRAIL-mediated apoptosis
Increases reverse glutamine metabolism in pancreatic cancer cells

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2,933

Medchemexpress LLC Leb-03-146 | 2858812-91-4 | 98.1% | C46H57N11O8 | 1 MG

LEB-03-146 is a deubiquitinase-targeting chimera (DUBTAC) that links AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 via a PEG2 linker. This compound is intended for research use only.

Demonstrates significant WEE1 stabilization in HEP3B hepatoma cancer cells.
Functions as a deubiquitinase-targeting chimera (DUBTAC).
Links AZD1775 (Adavosertib) to the OTUB1 recruiter EN523.

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2,934

Ambeed Methyl 5bromo2fluorobenzoate

Methyl 5-bromo-2-fluorobenzoate, 57381-59-6, 98%

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2,935

Ambeed 5Amino2methoxypyrimidine

5-Amino-2-methoxypyrimidine, 56621-89-7, 98%

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2,936

Ambeed Methanesulfonato 2dicyclohexyl

Methanesulfonato(2-dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II), 1599466-83-7, 98+%

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2,937

Medchemexpress LLC LM11A-31 5mg | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 5 MG

LM11A-31 is a small-molecule ligand and modulator of the p75 neurotrophin receptor (p75NTR) used in preclinical research of neurodegenerative diseases. It is orally active, brain-penetrant, and provided for in vitro and in vivo studies in solid and solution formats.

Small-molecule p75NTR modulator for neurodegeneration research.
Orally active and brain-penetrant in preclinical studies.
Available as a solid and as 10 mM solutions in DMSO for convenience.
Identified by CAS 102562-74-3 and molecular formula C12H25N3O2.
High reported purity (~99.9%) suitable for research applications.
Commonly supplied in small research pack sizes such as 5 mg.

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2,938

Medchemexpress LLC HCV-IN-31 | 1998705-62-6 | 99.7% | 312.30 | 1 ML

HCV-IN-31 is a potent HCV inhibitor. It has an EC50/EC95 of 15.7 μM for HCV replicon, making it suitable for research applications related to hepatitis C virus inhibition.

Functions as an HCV inhibitor
Exhibits an EC50/EC95 of 15.7 μM for HCV replicon
Solid appearance
Color ranges from white to off-white
Purity of 99.7%
Molecular weight of 312.30
Intended for research use only

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2,939

Medchemexpress LLC LM11A-31 (dihydrochloride) | 1243259-19-9 | 99.9% | 316.27 | 25 MG

LM11A-31 dihydrochloride is a non-peptide p75NTR (neurotrophin receptor p75) modulator and an orally active, potent proNGF (nerve growth factor) antagonist. It is an amino acid derivative that readily crosses the blood-brain barrier and inhibits p75-mediated cell death. This compound has been shown to reverse cholinergic neurite dystrophy in mouse models of Alzheimer's disease during mid- to late-stage disease progression. It is intended for research use only and is not sold to patients.

Non-peptide p75NTR modulator
Orally active and potent proNGF antagonist
Amino acid derivative with high blood-brain barrier permeability
Blocks p75-mediated cell death
Reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models
Mitigates proNGF accumulation and preserves BRB integrity in animal models

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2,940

Medchemexpress LLC AL-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 1 MG

AL-611 is an HCV NS5B polymerase inhibitor with an EC50 of 5 nM. It targets HCV Protease and is involved in anti-infection and metabolic enzyme/protease pathways.

HCV NS5B polymerase inhibitor (EC50 = 5 nM)
Targets HCV Protease
Involved in anti-infection and metabolic enzyme/protease pathways
Molecular weight: 614.54
Soluble in DMSO at 125 mg/mL (requires ultrasonication)
Appears as a white to off-white solid
Used in research for chronic Hepatitis C treatment

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Quinolines and derivatives

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Apexbio Technology LLC [Ser25] Protein Kinase C (19-31) 136795-05-6 5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SRI 6409-94 | 127697-58-9 | 99.25% | 379.49 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pyrroloquinoline quinone disodium salt | 122628-50-6 | 98.0% | 374.17 g/mol | C14H4N2Na2O8 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CR-1-31-B | 1352914-52-3 | >98.38% | 507.53 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Leb-03-146 | 2858812-91-4 | 98.1% | C46H57N11O8 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC LM11A-31 5mg | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HCV-IN-31 | 1998705-62-6 | 99.7% | 312.30 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC LM11A-31 (dihydrochloride) | 1243259-19-9 | 99.9% | 316.27 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AL-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More